Primary acquired idiopathic sideroblastic anaemias : a report of 4 cases and review of literature

Abstract EN

Sideroblastic anemias are rare conditions, in which the red cells production will be impaired, due to defect in iron metabolism.

They are classified as hereditary or acquired form.

The acquired form may be assodated with drugs, malignant diseases, connective tissue diseases or the cause can not be identified (idiopathic).

The aim of this paper is to report four cases ofprimary acquiredform of sideroblastic anemia that were seen in Basrah.

Tour patients with primary acquired sideroblastic anemias (PASA.) were reported, 3 of them were females, their ages ranged from 18-56 years.

All of them presented with severe anemia.

They were of hypochromic microcytic type in 2 patients, < & dimorphic type in other 2 patients.

Bone marrow examinations revealed pathological ring sideroblasts in all patients, and only one patient had marked dysplastic changes on bone marrow examination.

This patient became transfusion dependent and she would possibly carry a risk of developing acute myeloid leukemia.