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Role of kidney biomarkers of chronic kidney disease : an update
Joint Authors
Source
Saudi Journal of Biological Sciences
Issue
Vol. 21, Issue 4 (30 Sep. 2014), pp.294-299, 6 p.
Publisher
Publication Date
2014-09-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Chronic kidney disease (CKD) is a progressive pathological condition marked by deteriorating renal function over time.
Diagnostic of kidney disease depend on serum creatinine level and glomerular filtration rate which is detectable when kidney function become half.
The detection of kidney damage in an early stage needs robust biomarkers.
Biomarkers allow monitoring the disease progression at initial stages of disease.
On the onset of impairment in cellular organization there is perturbation in signaling molecules which are either up-regulated or down-regulated and act as an indicator or biomarker of diseased stage.
This review compiled the cell signaling of different kidney biomarkers associated with the onset of chronic kidney diseases.
Delay in diagnosis of CKD will cause deterioration of nephron function which leads to End stage renal disease and at that point patients require dialysis or kidney transplant.
Detailed information on the complex network in signaling pathway leading to a coordinated pattern of gene expression and regulation in CKD will undoubtedly provide important clues to develop novel prognostic and therapeutic strategies for CKD.
American Psychological Association (APA)
Khan, Zeba& Pandey, Manoj. 2014. Role of kidney biomarkers of chronic kidney disease : an update. Saudi Journal of Biological Sciences،Vol. 21, no. 4, pp.294-299.
https://search.emarefa.net/detail/BIM-393784
Modern Language Association (MLA)
Khan, Zeba& Pandey, Manoj. Role of kidney biomarkers of chronic kidney disease : an update. Saudi Journal of Biological Sciences Vol. 21, no. 4 (Sep. 2014), pp.294-299.
https://search.emarefa.net/detail/BIM-393784
American Medical Association (AMA)
Khan, Zeba& Pandey, Manoj. Role of kidney biomarkers of chronic kidney disease : an update. Saudi Journal of Biological Sciences. 2014. Vol. 21, no. 4, pp.294-299.
https://search.emarefa.net/detail/BIM-393784
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 298-299
Record ID
BIM-393784