Extensive homologous recombination in classical swine fever virus : a re-evaluation of homologous recombination events in the strain AF407339
Joint Authors
Source
Saudi Journal of Biological Sciences
Issue
Vol. 21, Issue 4 (30 Sep. 2014), pp.311-316, 6 p.
Publisher
Publication Date
2014-09-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Abstract EN
In this short report, the genome-wide homologous recombination events were re-evaluated for classical swine fever virus (CSFV) strain AF407339.
We challenged a previous study which suggested only one recombination event in AF407339 based on 25 CSFV genomes.
Through our reanalysis on the 25 genomes in the previous study and the 41 genomes used in the present study, we argued that there should be possibly at least two clear recombination events happening in AF407339 through genome-wide scanning.
The reasons for identifying only one recombination event in the previous study might be due to the limited number of available CSFV genome sequences at that time and the limited usage of detection methods.
In contrast, as identified by most detection methods using all available CSFV genome sequences, two major recombination events were found at the starting and ending zones of the genome AF407339, respectively.
The first one has two parents AF333000 (minor) and AY554397 (major) with beginning and ending breakpoints located at 19 and 607 nt of the genome respectively.
The second one has two parents AF531433 (minor) and GQ902941 (major) with beginning and ending breakpoints at 8397 and 11,078 nt of the genome respectively.
Phylogenetic incongruence analysis using neighbor-joining algorithm with 1000 bootstrapping replicates further supported the existence of these two recombination events.
In addition, we also identified additional 18 recombination events on the available CSFV strains.
American Psychological Association (APA)
Chen, Youhua& Chen, You Fang. 2014. Extensive homologous recombination in classical swine fever virus : a re-evaluation of homologous recombination events in the strain AF407339. Saudi Journal of Biological Sciences،Vol. 21, no. 4, pp.311-316.
https://search.emarefa.net/detail/BIM-393871
Modern Language Association (MLA)
Chen, Youhua& Chen, You Fang. Extensive homologous recombination in classical swine fever virus : a re-evaluation of homologous recombination events in the strain AF407339. Saudi Journal of Biological Sciences Vol. 21, no. 4 (Sep. 2014), pp.311-316.
https://search.emarefa.net/detail/BIM-393871
American Medical Association (AMA)
Chen, Youhua& Chen, You Fang. Extensive homologous recombination in classical swine fever virus : a re-evaluation of homologous recombination events in the strain AF407339. Saudi Journal of Biological Sciences. 2014. Vol. 21, no. 4, pp.311-316.
https://search.emarefa.net/detail/BIM-393871
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references: p. 315-316
Record ID
BIM-393871