Denovo post renal transplantation inflammatory bowel diseas
Joint Authors
Nampoory, Mangalathillam R. N.
al-Sisi, Ashraf
al-Utaybi, T.
Halim, M. A.
al-Sayyid, A.
Nair, Prasad
Said, Tariq
Balaha, M. A.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 19, Issue 4 (31 Aug. 2008), pp.624-626, 3 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2008-08-31
Country of Publication
Saudi Arabia
No. of Pages
3
Main Subjects
Topics
Abstract EN
Post-renal transplant de-novo inflammatory bowel disease (IBD) may develop despite the presence of mycophenolate mofetil (MMF), a drug used for treatment of IBD, in the immunosuppressive regimen.
A 39-year-old man received live unrelated renal transplant, and was started postoperatively on prednisolone, MMF, and tacrolimus, which was changed to sirolimus when he developed diabetes mellitus two months post-transplant.
Nine months post-transplant, the patient developed recurrent attacks of bloody diarrhea and ischio-rectal abscesses complicated by anal fistulae not responding to routine surgical treatment.
Colonoscopy diagnosed IBD, a Crohn's disease-like pattern.
The patient was treated with steroids and 5-aminosalicylic acid (5ASA) in addition to a two months course of ciprofloxacin and metronidazole.
He became asymptomatic and rectal lesions healed within one month of treatment.
The patient continued to be asymptomatic, and he maintained normal graft function on the same immunosuppressive treatment in addition to 5-ASA.
We conclude that de-novo IBD disease can develop in renal transplant recipients in spite of immunosuppressive therapy including MMF.
American Psychological Association (APA)
Halim, M. A.& al-Utaybi, T.& al-Sisi, Ashraf& al-Sayyid, A.& Nair, Prasad& Said, Tariq…[et al.]. 2008. Denovo post renal transplantation inflammatory bowel diseas. Saudi Journal of Kidney Diseases and Transplantation،Vol. 19, no. 4, pp.624-626.
https://search.emarefa.net/detail/BIM-39400
Modern Language Association (MLA)
Halim, M. A.…[et al.]. Denovo post renal transplantation inflammatory bowel diseas. Saudi Journal of Kidney Diseases and Transplantation Vol. 19, no. 4 (Dec. 2008), pp.624-626.
https://search.emarefa.net/detail/BIM-39400
American Medical Association (AMA)
Halim, M. A.& al-Utaybi, T.& al-Sisi, Ashraf& al-Sayyid, A.& Nair, Prasad& Said, Tariq…[et al.]. Denovo post renal transplantation inflammatory bowel diseas. Saudi Journal of Kidney Diseases and Transplantation. 2008. Vol. 19, no. 4, pp.624-626.
https://search.emarefa.net/detail/BIM-39400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 626
Record ID
BIM-39400