Clinicopathological study of primary nephrotic syndrome in the western area of Saudi Arabia

Abstract EN

The clinicopathological features 142 cases of childhood nep-hrotic syndrome (N.S.) were studied in the King Abdulaziz University Hos-pital (K.A.U.H.) and the National Guard Hospital (N.G.H.) during the period 1983-1992.

The clinical and laboratory findings were sim؛)ar to those described in other parts 0؛ the world.

Fifty two (36.62%) renal biopsies have been done.

Minimal change nephrotic syndrome (M.C.N.S.) is the commonest, it constitutes 28.8% of those biopsied.

It has the highest ratio of the total (73.9%) compared to Focal Segmental Glomerosclerosis (F.S.G.N.) (4.93%), mesangioproliferative (M.S.P.G.N.) (5.6%), mem-branous proliferative (M.P.G.N.) (4.93%), membranous (M.G.N.) (2.1%), and congenital nephrotic syndrome (C.N.S.) in (5.6%) Familial nephrotic syndrome (F.N.S.) was found in (2.8%).

The relative frequeney of pathological types of nephrotic syndrome in the western province of Saudi Arabia is similar to that reported in most other countries except that the congenital type is more prevalent in this study.

However, the frequeney of pathological types are different from those reported in the central part of Saudi Arabia.