The effect of cold ischemia time on delayed graft function and acute rejection in kidney transplantation
Joint Authors
Colak, Hulya
Sert, Ismail
Karaca, Cezmi
Tugmen, Cem
Dogan, Sait Murat
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 5 (31 Oct. 2014), pp.960-966, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-10-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
- Patients
- Kidneys
- Penal functions
- Medical examinations
- Coronary heart diseases
- Organ transplantation
- Complications(Medicine)
Abstract EN
The objective of this study is to evaluate the impact of cold ischemia time (CIT) on delayed graft function (DGF) and acute rejection (AR) among deceased donor kidney transplant recipients.
The medical records of 111 patients who underwent kidney transplantation from deceased donors between November 1994 and July 2009 were retrospectively analyzed.
DGF was observed in 54 % of the patients and the prevalence of AR in the first year after transplantation was 9.9 %.
The incidence of DGF was higher among patients with longer CIT.
There was no correlation between CIT and AR episodes.
Higher body weight of recipients and donors, history of prior blood transfusion and advanced donor age were related with DGF.
Patients with DGF had higher serum creatinine levels at the first, third and fifth years.
There was a negative correlation between recipient body weight and creatinine clearance at the first year.
CIT has an important role in the development of DGF as a modifiable risk factor.
Moreover, donors with advanced age and higher body weight as well as recipients with higher body weight and history of blood transfusions are at risk for the development of DGF.
Prevention of DGF may help to improve graft function at the first, third and fifth years and shorten the hospital stay.
American Psychological Association (APA)
Sert, Ismail& Colak, Hulya& Tugmen, Cem& Dogan, Sait Murat& Karaca, Cezmi. 2014. The effect of cold ischemia time on delayed graft function and acute rejection in kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 5, pp.960-966.
https://search.emarefa.net/detail/BIM-400129
Modern Language Association (MLA)
Sert, Ismail…[et al.]. The effect of cold ischemia time on delayed graft function and acute rejection in kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 5 (2014), pp.960-966.
https://search.emarefa.net/detail/BIM-400129
American Medical Association (AMA)
Sert, Ismail& Colak, Hulya& Tugmen, Cem& Dogan, Sait Murat& Karaca, Cezmi. The effect of cold ischemia time on delayed graft function and acute rejection in kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 5, pp.960-966.
https://search.emarefa.net/detail/BIM-400129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 965-966
Record ID
BIM-400129