Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients
Joint Authors
Sani, Dawlat
al-Sawi, Abd al-Basit
al-Shawi, Yasir
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 5 (31 Oct. 2014), pp.967-973, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-10-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
Hepcidin may play a critical role in the response of patients with anemia to iron and erythropoiesis-stimulating agent therapy.
To evaluate the factors affecting serum hepcidin levels and their relation to other indexes of anemia, iron metabolism and inflammation, as well as the dose of erythropoietin, we studied 80 maintenance hemodialysis (MHD) patients treated with recombinant human erythropoietin and their serum hepcidin levels were specifically measured by using a competitive enzyme-linked immunosorbent assay.
In linear regression analysis, ferritin was found to be a significant predictor of hepcidin levels in all the study patients.
In the absence of apparent inflammation, serum hepcidin levels correlated exclusively with ferritin levels in MHD patients, and it was also an independent marker of inflammation as highly sensitive Creactive protein.
American Psychological Association (APA)
Sani, Dawlat& al-Sawi, Abd al-Basit& al-Shawi, Yasir. 2014. Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 5, pp.967-973.
https://search.emarefa.net/detail/BIM-400141
Modern Language Association (MLA)
Sani, Dawlat…[et al.]. Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 5 (2014), pp.967-973.
https://search.emarefa.net/detail/BIM-400141
American Medical Association (AMA)
Sani, Dawlat& al-Sawi, Abd al-Basit& al-Shawi, Yasir. Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 5, pp.967-973.
https://search.emarefa.net/detail/BIM-400141
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 972-973
Record ID
BIM-400141