Effect of whole body gamma-irradiation exposure on liver arginase activity in albino rats

Abstract EN

The effect of whole body gamma-irradiation exposure on liver arginase activity and its relationship to urea concentrations in plasma and urine has been studied in albino rats.

Radiation exposure caused significant increases in urea levels in both plasma and urine.

These increases are dependant on the radiation dose levels.

Arginase activity (which controls the final stage in urea biosynthesis) has been shown to increase and this provides an explanation for the increased urea levels in plasma and urine after irradiation.