Kinetic and thermodynamic investigations of the reaction between metoclopramide hydrochloride and para-dimethylaminobenzaldehyde
Author
Said, Abd al-Samad Muhammad Ali
Source
Iraqi National Journal of Chemistry
Issue
Vol. 2011, Issue 44 (31 Dec. 2011), pp.516-525, 10 p.
Publisher
University of Babylon College of Sciences
Publication Date
2011-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract AR
تضمن البحث دراسة حركية ثرموداينميكية لتفاعل عقار ميتوكلوبراميد مع بارا-ثنائي مثيل بنزالديهايد في وسط حامضي و مذيب الماء / الكحول.
و اثبتت الدراسة أن التفاعل عكسي من الرتبة الأولى بالاعتماد على تركيز البنزالديهايد و من الرتبة صفر باللإعتماد على تركيز الدواء.
كما تم إيجاد ثابت السرعة، طاقة التنشيط، معامل ما قبل الأس و باقي القيم الثرموداينميكية للتنشيط للتفاعلين الأمامي و العكسي.
كذلك تم حساب القيم الثرموداينميكية القياسية للتفاعل التي شملت ثابت التوازن، الطاقة الحرة لجبس، الإنثالبي و الإنتروبي.
Abstract EN
Kinetic study of the condensation reaction of metoclopramide drug with paradimethylaminobenzaldehyde (DAB) in weakly acidic EtOH / H2O has been investigated.
A reversible first order reaction with respect to DAB and zero order with respect to metoclopramide has been observed.
The rate constants, activation energies, preexponential factors, and other related thermodynamic functions of activation for both forward and reverse reactions have been determined.
Standard thermodynamic parameters including equilibrium constant, ΔGo, ΔHo, and ΔSo have been calculated.
American Psychological Association (APA)
Said, Abd al-Samad Muhammad Ali. 2011. Kinetic and thermodynamic investigations of the reaction between metoclopramide hydrochloride and para-dimethylaminobenzaldehyde. Iraqi National Journal of Chemistry،Vol. 2011, no. 44, pp.516-525.
https://search.emarefa.net/detail/BIM-406629
Modern Language Association (MLA)
Said, Abd al-Samad Muhammad Ali. Kinetic and thermodynamic investigations of the reaction between metoclopramide hydrochloride and para-dimethylaminobenzaldehyde. Iraqi National Journal of Chemistry No. 44 (2011), pp.516-525.
https://search.emarefa.net/detail/BIM-406629
American Medical Association (AMA)
Said, Abd al-Samad Muhammad Ali. Kinetic and thermodynamic investigations of the reaction between metoclopramide hydrochloride and para-dimethylaminobenzaldehyde. Iraqi National Journal of Chemistry. 2011. Vol. 2011, no. 44, pp.516-525.
https://search.emarefa.net/detail/BIM-406629
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 525
Record ID
BIM-406629