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Goodpasture's syndrome : four case reports
Joint Authors
Ramadani, Benyounes
Hachim, K.
Rizqi, Hasna
Salam, N.
Fadili, W.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 18, Issue 2 (30 Apr. 2007), pp.235-238, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2007-04-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Patients
- Case studies
- Arteries
- Kidneys
- Diseases
- Autoimmune diseases
- Hemodialysis
- Wounds and injuries
- Blood
- Anemia
- Kidney failure
Abstract EN
Goodpasture's syndrome (GPS) is a rare but severe immunological disease, which is characterised by rapidly progressive glomerulonephritis and intraalveolar hemorrhage (IAH) with the presence of anti-glomerular basement membrane (GBM) antibodies.
We report four cases of GP's syndrome referred to the nephrology unit at Ibn Rochd UHC in Casablanca from January 1995 to December 2003.
All patients had rapidly progressive glomerulonephritis (RPGN) with proteinuria and microscopic hematuria.
Elevated blood pressure was noted in one case.
IAH was manifested as hemoptysis in two cases, radiological signs in three cases and confirmed by broncho-alveolar lavage in all cases.
Laboratory assessment revealed anemia in all cases.
Renal biopsy showed extracapillary glomerulonephritis with linear deposits of IgG along the GBM.
Renal failure was severe and hemodialysis was required in all cases.
All patients were treated with prednisone and cyclophosphamide and none recovered renal function.
Two patients died due to severe lung hemorrhage.
American Psychological Association (APA)
Salam, N.& Rizqi, Hasna& Fadili, W.& Hachim, K.& Ramadani, Benyounes. 2007. Goodpasture's syndrome : four case reports. Saudi Journal of Kidney Diseases and Transplantation،Vol. 18, no. 2, pp.235-238.
https://search.emarefa.net/detail/BIM-40688
Modern Language Association (MLA)
Salam, N.…[et al.]. Goodpasture's syndrome : four case reports. Saudi Journal of Kidney Diseases and Transplantation Vol. 18, no. 2 (Dec. 2007), pp.235-238.
https://search.emarefa.net/detail/BIM-40688
American Medical Association (AMA)
Salam, N.& Rizqi, Hasna& Fadili, W.& Hachim, K.& Ramadani, Benyounes. Goodpasture's syndrome : four case reports. Saudi Journal of Kidney Diseases and Transplantation. 2007. Vol. 18, no. 2, pp.235-238.
https://search.emarefa.net/detail/BIM-40688
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 238
Record ID
BIM-40688