Study of the serum concentrations of tnf-α and interleukin-2 in chronically patients with hepatitis b and c

Abstract EN

Viral hepatitis is an important endemic disease in Iraq, this work was curried in the period between January and June 2007.

And was aimed to evaluate the serum levels of cytokines in the chronic patients.

Obtained results showed that their is a clear elevation in the levels TNF- in HBsAg positive group (211.27 ± 28 pg / ml), and (189.77 ± 23.5 pg / ml) in patients with HCV in comparison to control group (59.45 ± 22 pg / ml).

also levels of IL-2 recorded a remarkable increment, In HBsAg positive group (101.47± 29 pg/ml), and in HCV patients (88.78 ± 19.5 pg / ml ) in comparison to control group (62.22 ± 14 pg / ml).

These results indicate the predominant role of Th-2 than Th-1 which lead to chronicity of the disease in those patients.