Evaluation of the efficacy of contractubex gel in plane wart treatment

Abstract EN

Treatment of plane warts is a problematic.

Methods such as a combination of salicylic acid with lactic acid lotion, cryotherapy and cauterization are used but they are associated with high recurrence rate, risk of scar, pain and high cost.

In addition, treatment with topical tretinoin lotion causes an irritant contact dermatitis that limited its use.

Contractubex gel consists of heparin sodium 5000 I.U, extre cepa 10g, allantoin 1.0g in water-soluble, fat free gel, exerts a softening and smoothing effect on indurated, hypertrophic, painful and cosmetically disfiguring scar tissue.

In this study, the efficacy of contractubex gel in treatment of plane warts was evaluated and compared with 0.05 % tretinoin lotion treatment.

The results, after six weeks follow up revealed that up to 79.4 % of the lesions in contractubex gel treated group diapered versus 20.6 % of the lesions in tretinoin treated group.

This modality of treatment seems to be superior to tretinoin lotion in the treatment of plane warts and even the common type, which is due to high efficacy of contractubex gel associated with low incidence of side effects.

This is the first use for this drug in the treatment of viral warts.