Retrograde comparative study for the outcome of fresh versus thawed embryo transfer in ICSI cycles

Abstract EN

Objective : published studies found that the transfer of fresh compared with frozen / thawed embryos result in higher pregnancy rate.

Transfer of thawed embryos may have lower rates of preterm birth, perinatal mortality and low birth weight than transfer of fresh embryos (1, 2).

Aim : to evaluate the outcome of fresh versus thawed-frozen embryo transfer on pregnancy rate and live birth rate in the international Islamic center for population studies and researches (IICPSR) in assisted reproductive technology (ART) unit.

Setting : This is a retrospective analytical study that was conducted at the ART unit, IICPSR, Al-Azhar University, Cairo, Egypt.

Methods : Data of 500 cases underwent intercytoplasmic sperm injection (ICSI) fresh embryo transfer (ET) and 214 cases underwent frozen-thawed ET in the period from 2009 till the end of 2011 have been analyzed using SPSS version 11.5.

Results : Positive biochemical pregnancy rates were significantly higher in fresh ET (30.2 %) than in frozen ET (8.5 %).

It was higher in slow freezing embryos transfer (1.7 %) than in vitrification (0.3 %).

The comparison between live birth in fresh, vitrification and slow freezing ET was significantly valuable.

Live birth rate in fresh ET was (27.4 %).

Conclusion : Positive biochemical pregnancy rates were more in fresh ET than frozen ET.

It was more in slow freezing ET than in vitrification.

Live birth rate was more in fresh ET than thawed ET.

In slow freezing, it was 8.3 %.

On the other hand, there wasn't any live birth in vitrification.