Outcome of intracytoplasmic sperm injection (ICSI)‎ using sperm from fresh ejaculate versus testicular sperm (TESE)‎ from the same infertile man with severe oligospermia, athenospermia and teratospermia in the same ICSI cycle

Abstract EN

Objective : The aim of this study is to Compare ICSI result, fertilization rate, Cleavage rate, quality and number of embryos and Pregnancy rate using either fresh ejaculate sperm or testicular sperm in the same infertile man with Severe Oligospermia, Athenospermia and Teratospermia.

Patients and Methods : Prospective study, on Seventy five couples with male factor infertility and normal wives was conducted at the assisted reproduction unit at the International Islamic Centre for Population Studies and Research (IICPSR), Al-Azhar University, Egypt during the period from January 2010 to May 2011.

All cases were clinically evaluated and eligible for analysis by using inclusion and exclusion criteria.

In these disorders, testicular biopsy is normal and the sperm count adequate for doing ICSI absent.

All studied men were subjected to : Ejaculate sperm and Testicular Sperm evaluation.

ICSI was performed simultaneously of different oocytes from the same woman using an ejaculate sperm and testicular sperm from the same husband.

ICSI outcomes were compared in the two sequential attempts performed, respectively.

Number and quality of oocyte, fertilization rates, rate of embryo cleavage and pregnancy rate were recorded.

Results : This study showed that the use of testicular sperm can improve fertilization rate and pregnancy rate compared to ejaculated sperm in ICSI.

It was concluded that the use of testicular spermatozoa in ICSI should be considered better than ejaculated spermatozoa in men with severe oligospermia, asthenospermia or teratospermia.