Environmental benign synthesis, characterization and antimicrobial activity of some imidazole derivatives

Joint Authors

Rathore, Dimple K.
Sharma, V. K.

Source

Iraqi National Journal of Chemistry

Issue

Vol. 2014, Issue 54 (30 Jun. 2014), pp.208-216, 9 p.

Publisher

University of Babylon College of Sciences

Publication Date

2014-06-30

Country of Publication

Iraq

No. of Pages

9

Main Subjects

Chemistry

Abstract AR

تم تحضير سلسلة مشتقات الأيمدازول بواسطة التكثيف مع مختلف مشتقات aminothiazole-2 and one-(4H)5 يا و الثايويوريا الناتج من تفاعل-2-thiazol)-9-phenyl-8 substituted) -9,6-(yl-2-thiazol)-9-phenyl-8 and substituted (f-a)3 one-(3H)2-purin-1H-dihydro-9,6-(yl ((f-a)4 thione-(3H)2-purine-1H-dihydro نتائج اطياف H NMR and MASS ,IR تؤكد ان المركبات المحضرة من التفاعل اعلاه جديدة.

و كل التفاعلات تم اجراؤها خارج تاثير الظروف الخارجية وتؤكد على ان التفاعلات بكفاءة عالية و سريعة باستخدام تحاليل المايكرويف، و تم تطبيق هده المشتقات لغرض ايجاد فعاليتها البايلوجية.

Abstract EN

A series of imidazole derivatives by condensation of, differently substituted 4-benzylidene-2-phenyloxazol-5(4H)-one and 2-aminothiazole, which on further reaction with Urea and Thiourea produces the final products (substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purin-2(3H)-one 3(a-f) and substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purine-2(3H)-thione 4(a-f)).

IR, H1 NMR and MASS spectral data confirmed the structure of the newly synthesized compounds.

All the reactions were carried out by environmental benign, efficient and extremely fast procedure Microwave synthesis.

The derivatives of these moieties were evaluated for antimicrobial activity.

American Psychological Association (APA)

Rathore, Dimple K.& Sharma, V. K.. 2014. Environmental benign synthesis, characterization and antimicrobial activity of some imidazole derivatives. Iraqi National Journal of Chemistry،Vol. 2014, no. 54, pp.208-216.
https://search.emarefa.net/detail/BIM-410855

Modern Language Association (MLA)

Rathore, Dimple K.& Sharma, V. K.. Environmental benign synthesis, characterization and antimicrobial activity of some imidazole derivatives. Iraqi National Journal of Chemistry No. 54 (2014), pp.208-216.
https://search.emarefa.net/detail/BIM-410855

American Medical Association (AMA)

Rathore, Dimple K.& Sharma, V. K.. Environmental benign synthesis, characterization and antimicrobial activity of some imidazole derivatives. Iraqi National Journal of Chemistry. 2014. Vol. 2014, no. 54, pp.208-216.
https://search.emarefa.net/detail/BIM-410855

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 215-216

Record ID

BIM-410855