Pelvic exenteration and composite sacral resection in the surgical treatment of locally recurrent rectal cancer
Joint Authors
Jamil, Muhammad
Khafaji, Midhat
Fakhr, Ibrahim
Mukhtar, Nadiyah
Jawad, Wail
Najm, Mustafa
Latif, Muhammad
Mansur, Uthman
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 26, Issue 3 (30 Sep. 2014), pp.167-173, 7 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2014-09-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background : The incidence of rectal cancer recurrence after surgery is 5-45 %.
Extended pelvic resection which entails En-bloc resection of the tumor and adjacent involved organs provides the only true possible curative option for patients with locally recurrent rectal cancer.
Aim : To evaluate the surgical and oncological outcome of such treatment.
Patients and Methods : Between 2006 and 2012 a consecutive series of 40 patients with locally recurrent rectal cancer underwent abdominosacral resection (ASR) in 18 patients, total pelvic exenteration with sacral resection in 10 patients and extended pelvic exenteration in 12 patients.
Patients with sacral resection were 28, with the level of sacral division at S2-3 interface in 10 patients, at S3-4 in 15 patients and S4-5 in 3 patients.
Results : Forty patients, male to female ratio 1.7 : 1, median age 45 years (range 25-65 years) underwent extended pelvic resection in the form of pelvic exenteration and abdominosacral resection.
Morbidity, re-admission and mortality rates were 55 %, 37.5 %, and 5 %, respectively.
Mortality occurred in 2 patients due to perineal flap sepsis and massive myocardial infarction.
A R0 and R1 sacral resection were achieved in 62.5 % and 37.5 %, respectively.
The 5-year overall survival rate was 22.6 % and the 4-year recurrence free survival was 31.8 %.
Conclusion : Extended pelvic resection as pelvic exenteration and sacral resection for locally recurrent rectal cancer are effective procedures with tolerable mortality rate and acceptable outcome.
The associated morbidity remains high and deserves vigilant follow up.
American Psychological Association (APA)
Jawad, Wail& Khafaji, Midhat& Jamil, Muhammad& Fakhr, Ibrahim& Najm, Mustafa& Mukhtar, Nadiyah…[et al.]. 2014. Pelvic exenteration and composite sacral resection in the surgical treatment of locally recurrent rectal cancer. Journal of the Egyptian National Cancer Institute،Vol. 26, no. 3, pp.167-173.
https://search.emarefa.net/detail/BIM-411979
Modern Language Association (MLA)
Jawad, Wail…[et al.]. Pelvic exenteration and composite sacral resection in the surgical treatment of locally recurrent rectal cancer. Journal of the Egyptian National Cancer Institute Vol. 26, no. 3 (2014), pp.167-173.
https://search.emarefa.net/detail/BIM-411979
American Medical Association (AMA)
Jawad, Wail& Khafaji, Midhat& Jamil, Muhammad& Fakhr, Ibrahim& Najm, Mustafa& Mukhtar, Nadiyah…[et al.]. Pelvic exenteration and composite sacral resection in the surgical treatment of locally recurrent rectal cancer. Journal of the Egyptian National Cancer Institute. 2014. Vol. 26, no. 3, pp.167-173.
https://search.emarefa.net/detail/BIM-411979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 172-173
Record ID
BIM-411979