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Serological and histopathological study of thyroid diseases : prospective study
Source
al-Kindy College Medical Journal
Issue
Vol. 10, Issue 1 (30 Jun. 2014), pp.62-64, 3 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2014-06-30
Country of Publication
Iraq
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background : Accurate detection of thyroid autoantibodies by enzyme linked immunosorbant assay technique namely thyroglobulin antibody, thyroid peroxides antibody is crucial in the differentiation of autoimmune thyroid disorders from other form of thyroid diseases.
Objective : Evaluation of the detection of thyroglobulin antibody and thyroid peroxides antibody in different thyroid diseases using enzyme linked immunosorbant assay technique.
Methods : Seventy-five patients admitted to Surgical Units of Baghdad Medical City Hospital for the period between "October 2010 to June 2011" they were waiting to do thyroidectomy.
They were chosen nonselectively for serological evaluation of above autoantibodies, and correlation of the results with histopathological diagnosis.
Results : Clinical results ; Colloid goiter is common cause of hyperthyroidism (19 were colloid goiter out of 30 total hyperthyroid patients) (63 %), and still common thyroid surgery (56 were colloid goiter out of 75 thyroid surgery) (75 %).
Histopathological results ; 56 cases (75 %) had colloid goiter, 9 patients had Graves' disease (12 %), and 3 had lymphocytic thyroiditis (4 %), 7 had thyroid neoplasia (both benign and malignant) (9 %).
The serological results ; Antibodies positive results were 6 patients (10.7 %) in colloid goiter (p- > 0.05), 6 patients (66 %) and 1 patient (33 %) for GD, and lymphocytic thyroiditis respectively(P- < 0.05)., while its all were negative in thyroid neoplasia.
Conclusion : Serum thyroid autoantibodies determination is valuable test in clinical practice of autoimmune thyroid diseases.
American Psychological Association (APA)
Muhammad, Muhammad Jassam. 2014. Serological and histopathological study of thyroid diseases : prospective study. al-Kindy College Medical Journal،Vol. 10, no. 1, pp.62-64.
https://search.emarefa.net/detail/BIM-413630
Modern Language Association (MLA)
Muhammad, Muhammad Jassam. Serological and histopathological study of thyroid diseases : prospective study. al-Kindy College Medical Journal Vol. 10, no. 1 (2014), pp.62-64.
https://search.emarefa.net/detail/BIM-413630
American Medical Association (AMA)
Muhammad, Muhammad Jassam. Serological and histopathological study of thyroid diseases : prospective study. al-Kindy College Medical Journal. 2014. Vol. 10, no. 1, pp.62-64.
https://search.emarefa.net/detail/BIM-413630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 64
Record ID
BIM-413630