Laryngeal amyloidosis : report of a new case and review of the literature
Joint Authors
Ammar, Haddu
Bouaity, Ibrahim
Darouassi, Yusuf
Touati, Muhammad Mliha
Chihani, Mahdi
Nadour, Karim
Source
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Issue
Vol. 15, Issue 3 (30 Sep. 2014), pp.263-265, 3 p.
Publisher
Egyptian Society of Ear Nose Throat and Allied Science
Publication Date
2014-09-30
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Topics
Abstract EN
Introduction : Amyloidosis is related to the extracellular deposition in various tissues of an amorphous amyloid substance.
Isolated laryngeal localization is very rare.
Observation : We report a case of localized laryngeal amyloidosis discovered during an isolated chronic dysphonia in a 45-year-old man, with no medical history, with no alcohol or tobacco intoxication.
The histological and immunohistochemical study and further examinations confirmed the diagnosis of localized laryngeal amyloidosis without systemic location.
The patient had a slight postoperative hoarseness that subsequently disappeared through speech therapy.
Discussion : The larynx remains a rare localization of amyloidosis.
It is the most common form of amyloidosis of the upper aero digestive tract.
Circumstances of discovery of laryngeal amyloidosis are dominated by hoarseness.
Laryngoscopy may falsely suggest a neoplastic disease.
Diagnosis is based upon histological examination with Congo red staining where amyloid deposits appear birefringent under polarized light.
Surgery is the mainstay of treatment of symptomatic laryngeal amyloidosis.
The survival of patients with laryngeal amyloidosis often exceeds ten years.
Conclusion : Laryngeal amyloidosis is essentially a local clinical form whose main symptom is dysphonia.
The treatment is usually based on local endoscopic procedures but may require a laryngectomy in advanced forms, associated with colchicine.
The prognosis is much better than systemic forms.
American Psychological Association (APA)
Bouaity, Ibrahim& Darouassi, Yusuf& Touati, Muhammad Mliha& Chihani, Mahdi& Nadour, Karim& Ammar, Haddu. 2014. Laryngeal amyloidosis : report of a new case and review of the literature. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 15, no. 3, pp.263-265.
https://search.emarefa.net/detail/BIM-422956
Modern Language Association (MLA)
Bouaity, Ibrahim…[et al.]. Laryngeal amyloidosis : report of a new case and review of the literature. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 15, no. 3 ( 2014), pp.263-265.
https://search.emarefa.net/detail/BIM-422956
American Medical Association (AMA)
Bouaity, Ibrahim& Darouassi, Yusuf& Touati, Muhammad Mliha& Chihani, Mahdi& Nadour, Karim& Ammar, Haddu. Laryngeal amyloidosis : report of a new case and review of the literature. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2014. Vol. 15, no. 3, pp.263-265.
https://search.emarefa.net/detail/BIM-422956
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 265
Record ID
BIM-422956