Aggrenox-Associated acute interstitial nephritis
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 17, Issue 1 (28 Feb. 2006), pp.50-53, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2006-02-28
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Acute interstitial nephritis (AIN) associated with the administration of the combination drug Aggrenox (acetylsalicylic acid 25 mg and dipyridamole 200 mg) has not been previously reported.
This is an 83-year-old man who presented with nausea, vomiting, weakness, and non-oliguric renal failure.
He started to have these complaints four days after starting Aggrenox one tablet daily.
There were no recent medication changes aside from the addition of Aggrenox.
The patient had normal serum creatinine one year prior to this event.
The renal biopsy showed acute interstitial nephritis (AIN).
The Aggrenox was stopped and the patient received saline intravenously.
The serum creatinine rose from 494 µmol / L on admission to a peak of 798 µmol / L on day 5 then decreased gradually to 179 µmol / L over four months.
The serologic investigations for common infectious and immune causes of AIN were negative.
In conclusion, this patient suffered AIN associated with the administration of Aggrenox and improved with discontinuation of this drug.
Further investigation may be needed to evaluate the prevalence of AIN associated with Aggrenox.
American Psychological Association (APA)
al-Huwaysh, Abd Allah K.. 2006. Aggrenox-Associated acute interstitial nephritis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 17, no. 1, pp.50-53.
https://search.emarefa.net/detail/BIM-42300
Modern Language Association (MLA)
al-Huwaysh, Abd Allah K.. Aggrenox-Associated acute interstitial nephritis. Saudi Journal of Kidney Diseases and Transplantation Vol. 17, no. 1 (Feb. 2006), pp.50-53.
https://search.emarefa.net/detail/BIM-42300
American Medical Association (AMA)
al-Huwaysh, Abd Allah K.. Aggrenox-Associated acute interstitial nephritis. Saudi Journal of Kidney Diseases and Transplantation. 2006. Vol. 17, no. 1, pp.50-53.
https://search.emarefa.net/detail/BIM-42300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 53
Record ID
BIM-42300