In vitro anthelmintic and cytotoxic activities of extracts from the stem barks of Berlinia confusa (C. Hoyle) and identification of its active constituents
Joint Authors
Lasisi, Adebayo
Idowu, Oluwafunmilayo
Source
Journal of Saudi Chemical Society
Issue
Vol. 18, Issue 6 (31 Dec. 2014), pp.939-944, 6 p.
Publisher
Publication Date
2014-12-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Phytochemical investigation of EtOAc extract from the stem bark of Berlinia confuse yielded a new and two known polysaturated monoacylglycerides characterised as 1-O-docosanoyl-sn-glyceride (3), 1-O-(13-methyltetradecanoyl)-sn-glycerol (4) and 1-O-pentadecacanoyl-snglycerol (5) ; along with the known compounds betulinic acid (1) and sitosteryl-b-D-glucoside (2).
The structures of these compounds were elucidated using analytical methods, including 1D and 2D-NMR together with MS spectroscopy.
The extracts and isolated compounds demonstrated concentration- dependent anthelmintic activities against Fusciola gigantica (liver flukes) and Taenia solium (tapeworm) at 10–100 mg / ml.
The extracts and isolated compounds were evaluated for cytotoxicity against a small panel of three human tumour cell lines.
American Psychological Association (APA)
Lasisi, Adebayo& Idowu, Oluwafunmilayo. 2014. In vitro anthelmintic and cytotoxic activities of extracts from the stem barks of Berlinia confusa (C. Hoyle) and identification of its active constituents. Journal of Saudi Chemical Society،Vol. 18, no. 6, pp.939-944.
https://search.emarefa.net/detail/BIM-427021
Modern Language Association (MLA)
Lasisi, Adebayo& Idowu, Oluwafunmilayo. In vitro anthelmintic and cytotoxic activities of extracts from the stem barks of Berlinia confusa (C. Hoyle) and identification of its active constituents. Journal of Saudi Chemical Society Vol. 18, no. 6 (2014), pp.939-944.
https://search.emarefa.net/detail/BIM-427021
American Medical Association (AMA)
Lasisi, Adebayo& Idowu, Oluwafunmilayo. In vitro anthelmintic and cytotoxic activities of extracts from the stem barks of Berlinia confusa (C. Hoyle) and identification of its active constituents. Journal of Saudi Chemical Society. 2014. Vol. 18, no. 6, pp.939-944.
https://search.emarefa.net/detail/BIM-427021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 944
Record ID
BIM-427021