Zolpidem dependency and withdrawal seizure : a case report study
Joint Authors
Javadi, Sayyid Alireza Haji Sayyid
Hajiali, Farid
Nassiri Asl, Marjan
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 16, Issue 11 (30 Nov. 2014), pp.1-3, 3 p.
Publisher
Publication Date
2014-11-30
Country of Publication
United Arab Emirates
No. of Pages
3
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Introduction : Zolpidem is a short acting inducer of sleep and thought to lack benzodiazepine properties such as anxiolysis, anticonvulsion, muscle relaxation and side effects such as dependency.
Recently, some cases of Zolpidem abuse and dependency have been reported.
In review of literature, we found that the lowest reported dosage of Zolpidem, which caused dependency, was 160 mg daily.
Case Presentation : We reported a 30-year-old unmarried Iranian woman with dysthymic disorder and chronic insomnia treated with Zolpidem irregularly.
She started to use Zolpidem with 5mg per day irregularly since a year ago but augmented its daily dosage gradually to 100 to 150 mg per day in divided doses.
After a period of 16 hours without taking Zolpidem she developed a withdrawal syndrome, with generalized tonic-clonic seizures for two times.
She was managed with supportive care and recovered completely.
Conclusions : Zolpidem dependency and withdrawal seizure can occur with a dosage under last reported doses.
Therefore, possibility of mentioned problems cannot be excluded at any dosage and physicians should pay more attention to potential of Zolpidem to create these adverse effects.
American Psychological Association (APA)
Javadi, Sayyid Alireza Haji Sayyid& Hajiali, Farid& Nassiri Asl, Marjan. 2014. Zolpidem dependency and withdrawal seizure : a case report study. Iranian Red Crescent Medical Journal،Vol. 16, no. 11, pp.1-3.
https://search.emarefa.net/detail/BIM-427920
Modern Language Association (MLA)
Javadi, Sayyid Alireza Haji Sayyid…[et al.]. Zolpidem dependency and withdrawal seizure : a case report study. Iranian Red Crescent Medical Journal Vol. 16, no. 11 (Nov. 2014), pp.1-3.
https://search.emarefa.net/detail/BIM-427920
American Medical Association (AMA)
Javadi, Sayyid Alireza Haji Sayyid& Hajiali, Farid& Nassiri Asl, Marjan. Zolpidem dependency and withdrawal seizure : a case report study. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 11, pp.1-3.
https://search.emarefa.net/detail/BIM-427920
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 3
Record ID
BIM-427920