Assessment of allograft function using diffusion-weighted magnetic resonance imaging in kidney transplant patients
Joint Authors
Kaul, Anupma
Sharma, Raj Kumar
Prasad, Narayan
Gupta, Amit
Gupta, Rakesh Kumar
Lal, Hira
Yadav, Abhishek
Bhadhuria, Dharmendra
Jaisuresh
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 6 (31 Dec. 2014), pp.1143-1147, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-12-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Developing a non-invasive method such as diffusion-weighted magnetic resonance imaging (DWMRI) could be used as a feasible and reproducible modality in the differential diagnosis of allograft dysfunction.
We assessed the functional status of the renal allograft by DWMRI and its applicability in assessment of graft dysfunction on all end-stage renal transplant patients who attained normal renal function on the 7th day post-transplantation.
Follow-up imaging of the recipient allograft was performed at the end of 90 and 180 days and in case of graft dysfunction.
Kidney biopsies were performed to correlate with the corresponding MRI.
The apparent diffusion coefficient (ADC) maps of the cortex and medulla were obtained by studying the DWMRI.
The ADC values were significantly lower in the medulla compared with the cortex in normal donor kidneys and normally functioning transplanted kidneys, while they decreased significantly when rejection occurred.
The reduction in ADC values occurred both in the cortex and in the medulla, and correlated with the degree of rejection on the kidney biopsies.
The ADC values increased significantly during the recovery from rejection.
We conclude that DWMRI can be beneficial in the diagnosis and follow-up of transplant patients during acute rejection.
American Psychological Association (APA)
Kaul, Anupma& Sharma, Raj Kumar& Gupta, Rakesh Kumar& Lal, Hira& Yadav, Abhishek& Bhadhuria, Dharmendra…[et al.]. 2014. Assessment of allograft function using diffusion-weighted magnetic resonance imaging in kidney transplant patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 6, pp.1143-1147.
https://search.emarefa.net/detail/BIM-431594
Modern Language Association (MLA)
Kaul, Anupma…[et al.]. Assessment of allograft function using diffusion-weighted magnetic resonance imaging in kidney transplant patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 6 (Dec. 2014), pp.1143-1147.
https://search.emarefa.net/detail/BIM-431594
American Medical Association (AMA)
Kaul, Anupma& Sharma, Raj Kumar& Gupta, Rakesh Kumar& Lal, Hira& Yadav, Abhishek& Bhadhuria, Dharmendra…[et al.]. Assessment of allograft function using diffusion-weighted magnetic resonance imaging in kidney transplant patients. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 6, pp.1143-1147.
https://search.emarefa.net/detail/BIM-431594
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1146-1147
Record ID
BIM-431594