Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose

Abstract EN

Overdose with calcium channel blockers is uncommon, but is associated with high mortality.

The management includes fluid resuscitation, calcium gluconate, glucagon, vasopressors, and high-dose insulin-euglycemia therapy.

We describe a rare case of massive overdose of lercanidipine with shock, refractory to conventional therapies and multi-organ failure.

Charcoal hemoperfusion with continuous venovenous hemodiafiltration was then used successfully and the patient showed remarkable recovery.