Acute tubulointerstitial nephristis and anterior uveitis (TINU syndrome) : a report of two cases
Joint Authors
Ramadani, Benyounes
Zayid, Driss
Hachim, K.
Mortajil, Fatimah
Rizqi, Hasna
Zahiri, K.
Skalli, Saida
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 17, Issue 3 (30 Jun. 2006), pp.386-389, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2006-06-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
TINU or Dobrin syndrome is a rare oculo-renal inflammatory condition which is comprised of acute idiopathic tubulointerstitial nephritis and uveitis.
We report here two female patients aged 35 and 44 years, who were admitted with severe renal failure of acute onset (serum creatinine of 607 and 310 Umol / L [Editor note : do you mean "µmol / L" ?] respectively) with the first patient requiring hemodialysis.
The cause of acute renal failure was unclear on clinical and laboratory assessment, and a percutaneous renal biopsy was performed which showed features of acute tubulointerstitial nephritis in both cases.
Both patients were started on oral steroids at a dose of 1 mg / kg / day.
There was progressive improvement of their renal function.
Three months later, the two patients presented with bilateral anterior uveitis requiring local corticosteroid therapy.
This was followed by total resolution of the uveitis.
The cause of the interstitial nephritis and the uveitis could not be identified in the two cases.
The renal function was normal in these patients after 24 and 27 months of follow-up, respectively.
Dobrin or TINU syndrome is rare, and must be considered in patients who present with acute tubular interstitial [Editor note : for consistency with the title, you may wish to replace this with "tubulointerstitial"] nephritis and anterior uveitis.
American Psychological Association (APA)
Mortajil, Fatimah& Rizqi, Hasna& Hachim, K.& Zahiri, K.& Ramadani, Benyounes& Zayid, Driss…[et al.]. 2006. Acute tubulointerstitial nephristis and anterior uveitis (TINU syndrome) : a report of two cases. Saudi Journal of Kidney Diseases and Transplantation،Vol. 17, no. 3, pp.386-389.
https://search.emarefa.net/detail/BIM-43503
Modern Language Association (MLA)
Ramadani, Benyounes…[et al.]. Acute tubulointerstitial nephristis and anterior uveitis (TINU syndrome) : a report of two cases. Saudi Journal of Kidney Diseases and Transplantation Vol. 17, no. 3 (Dec. 2006), pp.386-389.
https://search.emarefa.net/detail/BIM-43503
American Medical Association (AMA)
Mortajil, Fatimah& Rizqi, Hasna& Hachim, K.& Zahiri, K.& Ramadani, Benyounes& Zayid, Driss…[et al.]. Acute tubulointerstitial nephristis and anterior uveitis (TINU syndrome) : a report of two cases. Saudi Journal of Kidney Diseases and Transplantation. 2006. Vol. 17, no. 3, pp.386-389.
https://search.emarefa.net/detail/BIM-43503
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 389
Record ID
BIM-43503