Antibiotic resistance and extended spectrum beta-lactamases : types, epidemiology and treatment
Joint Authors
Kamal, Muhammad Amjad
Shaykh, Sibhghatulla
Jamali, Fatimah
Shakil, Shazi
Rizvi, Sayyid Mohd. Danish
Source
Saudi Journal of Biological Sciences
Issue
Vol. 22, Issue 1 (31 Mar. 2015), pp.90-101, 12 p.
Publisher
Publication Date
2015-03-31
Country of Publication
Saudi Arabia
No. of Pages
12
Main Subjects
Topics
Abstract EN
Antibiotic resistance is a problem of deep scientific concern both in hospital and community settings.
Rapid detection in clinical laboratories is essential for the judicious recognition of antimicrobial resistant organisms.
Production of extended-spectrum b-lactamases (ESBLs) is a significant resistance-mechanism that impedes the antimicrobial treatment of infections caused by Enterobacteriaceae and is a serious threat to the currently available antibiotic armory.
ESBLs are classified into several groups according to their amino acid sequence homology.
Proper infection control practices and barriers are essential to prevent spread and outbreaks of ESBL producing bacteria.
As bacteria have developed different strategies to counter the effects of antibiotics, the identification of the resistance mechanism may help in the discovery and design of new antimicrobial agents.
The carbapenems are widely regarded as the drugs of choice for the treatment of severe infections caused by ESBL-producing Enterobacteriaceae, although comparative clinical trials are scarce.
Hence, more expeditious diagnostic testing of ESBL-producing bacteria and the feasible modification of guidelines for community-onset bacteremia associated with different infections are prescribed.
American Psychological Association (APA)
Shaykh, Sibhghatulla& Jamali, Fatimah& Shakil, Shazi& Rizvi, Sayyid Mohd. Danish& Kamal, Muhammad Amjad. 2015. Antibiotic resistance and extended spectrum beta-lactamases : types, epidemiology and treatment. Saudi Journal of Biological Sciences،Vol. 22, no. 1, pp.90-101.
https://search.emarefa.net/detail/BIM-437370
Modern Language Association (MLA)
Shaykh, Sibhghatulla…[et al.]. Antibiotic resistance and extended spectrum beta-lactamases : types, epidemiology and treatment. Saudi Journal of Biological Sciences Vol. 22, no. 1 (2015), pp.90-101.
https://search.emarefa.net/detail/BIM-437370
American Medical Association (AMA)
Shaykh, Sibhghatulla& Jamali, Fatimah& Shakil, Shazi& Rizvi, Sayyid Mohd. Danish& Kamal, Muhammad Amjad. Antibiotic resistance and extended spectrum beta-lactamases : types, epidemiology and treatment. Saudi Journal of Biological Sciences. 2015. Vol. 22, no. 1, pp.90-101.
https://search.emarefa.net/detail/BIM-437370
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 98-101
Record ID
BIM-437370