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SAROTUP : Scanner and Reporter of Target-Unrelated Peptides
Joint Authors
Lin, Hao
Huang, Jian
Li, Shiyong
Guo, Feng-Biao
Ru, Beibei
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
As epitope mimics, mimotopes have been widely utilized in the study of epitope prediction and the development of new diagnostics, therapeutics, and vaccines.
Screening the random peptide libraries constructed with phage display or any other surface display technologies provides an efficient and convenient approach to acquire mimotopes.
However, target-unrelated peptides creep into mimotopes from time to time through binding to contaminants or other components of the screening system.
In this study, we present SAROTUP, a free web tool for scanning, reporting and excluding possible target-unrelated peptides from real mimotopes.
Preliminary tests show that SAROTUP is efficient and capable of improving the accuracy of mimotope-based epitope mapping.
It is also helpful for the development of mimotope-based diagnostics, therapeutics, and vaccines.
American Psychological Association (APA)
Huang, Jian& Ru, Beibei& Li, Shiyong& Lin, Hao& Guo, Feng-Biao. 2010. SAROTUP : Scanner and Reporter of Target-Unrelated Peptides. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-446422
Modern Language Association (MLA)
Huang, Jian…[et al.]. SAROTUP : Scanner and Reporter of Target-Unrelated Peptides. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-446422
American Medical Association (AMA)
Huang, Jian& Ru, Beibei& Li, Shiyong& Lin, Hao& Guo, Feng-Biao. SAROTUP : Scanner and Reporter of Target-Unrelated Peptides. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-446422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446422