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Coleopteran Antimicrobial Peptides : Prospects for Clinical Applications
Joint Authors
Kurata, Shoichiro
Goto, Akira
Ntwasa, Monde
Source
International Journal of Microbiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
Antimicrobial peptides (AMPs) are activated in response to septic injury and have important roles in vertebrate and invertebrate immune systems.
AMPs act directly against pathogens and have both wound healing and antitumor activities.
Although coleopterans comprise the largest and most diverse order of eukaryotes and occupy an earlier branch than Drosophila in the holometabolous lineage of insects, their immune system has not been studied extensively.
Initial research reports, however, indicate that coleopterans possess unique immune response mechanisms, and studies of these novel mechanisms may help to further elucidate innate immunity.
Recently, the complete genome sequence of Tribolium was published, boosting research on coleopteran immunity and leading to the identification of Tribolium AMPs that are shared by Drosophila and mammals, as well as other AMPs that are unique.
AMPs have potential applicability in the development of vaccines.
Here, we review coleopteran AMPs, their potential impact on clinical medicine, and the molecular basis of immune defense.
American Psychological Association (APA)
Ntwasa, Monde& Goto, Akira& Kurata, Shoichiro. 2012. Coleopteran Antimicrobial Peptides : Prospects for Clinical Applications. International Journal of Microbiology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-446427
Modern Language Association (MLA)
Ntwasa, Monde…[et al.]. Coleopteran Antimicrobial Peptides : Prospects for Clinical Applications. International Journal of Microbiology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-446427
American Medical Association (AMA)
Ntwasa, Monde& Goto, Akira& Kurata, Shoichiro. Coleopteran Antimicrobial Peptides : Prospects for Clinical Applications. International Journal of Microbiology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-446427
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446427