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Diagnostic and Therapeutic Challenges of a Large Pleural Inflammatory Myofibroblastic Tumor
Joint Authors
Steurer, Michael
Uprimny, Christian
Bodner, Johannes
Freund, Martin
Loeffler-Ragg, Judith
Zelger, Bettina
Kähler, Christian M.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We report a 48-year-old woman with a pleural pseudoneoplasm requiring different diagnostic and therapeutic strategies.
After initial presentation with increasing dyspnoea, temperature, dry cough, and interscapular pain diagnostic processing showed a large mediastinal mass with marked pleural effusion and high metabolic activity in the 18F-FDG-PET/CT.
Extensive CT-guided biopsy of the tumor reaching from the visceral pleura into the right upper lobe revealed no malignancy, but a marked inflammatory tissue reaction containing foam cells.
Initial empiric antibiotic therapy was temporarily successful.
However, in the further course the mass relapsed and was resistant to antibiotics and a corticosteroid trial.
With the working hypothesis of an inflammatory myofibroblastic tumor the patient underwent surgical tumor resection, finally confirming the suspected diagnosis.
Due to residual disease intravenous immunoglobulins were administered leading to sustained response.
This case with a pleural localisation of a large inflammatory pseudotumor with responsiveness to immunomodulation after incomplete resection extends the reported spectrum of thoracopulmonary manifestations of this rare entity.
American Psychological Association (APA)
Loeffler-Ragg, Judith& Bodner, Johannes& Freund, Martin& Steurer, Michael& Uprimny, Christian& Zelger, Bettina…[et al.]. 2012. Diagnostic and Therapeutic Challenges of a Large Pleural Inflammatory Myofibroblastic Tumor. Case Reports in Pulmonology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-446442
Modern Language Association (MLA)
Loeffler-Ragg, Judith…[et al.]. Diagnostic and Therapeutic Challenges of a Large Pleural Inflammatory Myofibroblastic Tumor. Case Reports in Pulmonology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-446442
American Medical Association (AMA)
Loeffler-Ragg, Judith& Bodner, Johannes& Freund, Martin& Steurer, Michael& Uprimny, Christian& Zelger, Bettina…[et al.]. Diagnostic and Therapeutic Challenges of a Large Pleural Inflammatory Myofibroblastic Tumor. Case Reports in Pulmonology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-446442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446442