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Importance and Limits of Ischemia in Renal Partial Surgery : Experimental and Clinical Research
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-07-15
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Introduction.
The objective is to determine the clinical and experimental evidences of the renal responses to warm and cold ischemia, kidney tolerability, and available practical techniques of protecting the kidney during nephron-sparing surgery.
Materials and methods.
Review of the English and non-English literature using MEDLINE, MD Consult, and urology textbooks.
Results and discussion.
There are three main mechanisms of ischemic renal injury, including persistent vasoconstriction with an abnormal endothelial cell compensatory response, tubular obstruction with backflow of urine, and reperfusion injury.
Controversy persists on the maximal kidney tolerability to warm ischemia (WI), which can be influenced by surgical technique, patient age, presence of collateral vascularization, indemnity of the arterial bed, and so forth.
Conclusions.
When WI time is expected to exceed from 20 to 30 minutes, especially in patients whose baseline medical characteristics put them at potentially higher, though unproven, risks of ischemic damage, local renal hypothermia should be used.
American Psychological Association (APA)
Secin, Fernando P.. 2008. Importance and Limits of Ischemia in Renal Partial Surgery : Experimental and Clinical Research. Advances in Urology،Vol. 2008, no. 2008, pp.1-10.
https://search.emarefa.net/detail/BIM-446466
Modern Language Association (MLA)
Secin, Fernando P.. Importance and Limits of Ischemia in Renal Partial Surgery : Experimental and Clinical Research. Advances in Urology No. 2008 (2008), pp.1-10.
https://search.emarefa.net/detail/BIM-446466
American Medical Association (AMA)
Secin, Fernando P.. Importance and Limits of Ischemia in Renal Partial Surgery : Experimental and Clinical Research. Advances in Urology. 2008. Vol. 2008, no. 2008, pp.1-10.
https://search.emarefa.net/detail/BIM-446466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446466