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Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies
Joint Authors
Pokorná, Michaela
Hatáková, Ladislava
Čáp, Michal
Palková, Zdena
Váchová, Libuše
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
During their development and aging on solid substrates, yeast giant colonies produce ammonia, which acts as a quorum sensing molecule.
Ammonia production is connected with alkalization of the surrounding medium and with extensive reprogramming of cell metabolism.
In addition, ammonia signaling is important for both horizontal (colony centre versus colony margin) and vertical (upper versus lower cell layers) colony differentiations.
The centre of an aging differentiated giant colony is thus composed of two major cell subpopulations, the subpopulation of long-living, metabolically active and stress-resistant cells that form the upper layers of the colony and the subpopulation of stress-sensitive starving cells in the colony interior.
Here, we show that microcolonies originating from one cell pass through similar developmental phases as giant colonies.
Microcolony differentiation is linked to ammonia signaling, and cells similar to the upper and lower cells of aged giant colonies are formed even in relatively young microcolonies.
A comparison of the properties of these cells revealed a number of features that are similar in microcolonies and giant colonies as well as a few that are only typical of chronologically aged giant colonies.
These findings show that colony age per se is not crucial for colony differentiation.
American Psychological Association (APA)
Váchová, Libuše& Hatáková, Ladislava& Čáp, Michal& Pokorná, Michaela& Palková, Zdena. 2013. Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-446472
Modern Language Association (MLA)
Váchová, Libuše…[et al.]. Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-446472
American Medical Association (AMA)
Váchová, Libuše& Hatáková, Ladislava& Čáp, Michal& Pokorná, Michaela& Palková, Zdena. Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-446472
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446472