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Development of Colonic Perforation during Calcium Polystyrene Sulfonate Administration : A Case Report
Joint Authors
Ohtsuka, Akihito
Takeuchi, Nobuhiro
Iida, Masato
Naba, Kazuyoshi
Yusuke, Nomura
Meda, Testuo
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A 90-year-old female complaining of severe upper abdominal pain was transferred to our institution.
The patient had been prescribed with calcium polystyrene sulfonate (CPS) for the treatment of hyperkalemia following myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) associated glomerulonephritis.
Physical examination revealed diffuse tenderness over the abdomen, with signs of peritoneal irritation.
Abdominal computed tomography (CT) revealed the retention of ascites, free air in the abdominal cavity, and the retention of hard stools in the left-sided colon.
The diagnosis of intestinal perforation was immediately confirmed; thereafter, the patient underwent emergency surgical treatment.
Surgical findings revealed a perforated site in the descending colon surrounded with hard stools.
Histopathology of the perforated colon revealed crystalline materials, suggestive of association with CPS.
CPS is a cation-exchange resin used to treat hyperkalemia; the major adverse effect in patients receiving CPS is constipation.
When CPS is administered to patients with frequent constipation or the elderly, the risk of intestinal perforation should be considered.
American Psychological Association (APA)
Takeuchi, Nobuhiro& Yusuke, Nomura& Meda, Testuo& Iida, Masato& Ohtsuka, Akihito& Naba, Kazuyoshi. 2013. Development of Colonic Perforation during Calcium Polystyrene Sulfonate Administration : A Case Report. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-446486
Modern Language Association (MLA)
Takeuchi, Nobuhiro…[et al.]. Development of Colonic Perforation during Calcium Polystyrene Sulfonate Administration : A Case Report. Case Reports in Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-446486
American Medical Association (AMA)
Takeuchi, Nobuhiro& Yusuke, Nomura& Meda, Testuo& Iida, Masato& Ohtsuka, Akihito& Naba, Kazuyoshi. Development of Colonic Perforation during Calcium Polystyrene Sulfonate Administration : A Case Report. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-446486
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446486