Adhesion and Proliferation of Human Periodontal Ligament Cells on Poly(2-methoxyethyl acrylate)
Joint Authors
Tanaka, Masaru
Kitakami, Erika
Aoki, Makiko
Ishihata, Hiroshi
Sato, Chikako
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-06
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Human periodontal ligament (PDL) cells obtained from extracted teeth are a potential cell source for tissue engineering.
We previously reported that poly(2-methoxyethyl acrylate) (PMEA) is highly biocompatible with human blood cells.
In this study, we investigated the adhesion, morphology, and proliferation of PDL cells on PMEA and other types of polymers to design an appropriate scaffold for tissue engineering.
PDL cells adhered and proliferated on all investigated polymer surfaces except for poly(2-hydroxyethyl methacrylate) and poly[(2-methacryloyloxyethyl phosphorylcholine)-co-(n-butyl methacrylate)].
The initial adhesion of the PDL cells on PMEA was comparable with that on polyethylene terephthalate (PET).
In addition, the PDL cells on PMEA spread well and exhibited proliferation behavior similar to that observed on PET.
In contrast, platelets hardly adhered to PMEA.
PMEA is therefore expected to be an excellent scaffold for tissue engineering and for culturing tissue-derived cells in a blood-rich environment.
American Psychological Association (APA)
Kitakami, Erika& Aoki, Makiko& Sato, Chikako& Ishihata, Hiroshi& Tanaka, Masaru. 2014. Adhesion and Proliferation of Human Periodontal Ligament Cells on Poly(2-methoxyethyl acrylate). BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-446489
Modern Language Association (MLA)
Kitakami, Erika…[et al.]. Adhesion and Proliferation of Human Periodontal Ligament Cells on Poly(2-methoxyethyl acrylate). BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-446489
American Medical Association (AMA)
Kitakami, Erika& Aoki, Makiko& Sato, Chikako& Ishihata, Hiroshi& Tanaka, Masaru. Adhesion and Proliferation of Human Periodontal Ligament Cells on Poly(2-methoxyethyl acrylate). BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-446489
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446489