Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature
Joint Authors
Zhurova, Mariia
Akabutu, John
Acker, Jason P.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Red blood cells (RBCs) from cord blood contain fetal hemoglobin that is predominant in newborns and, therefore, may be more appropriate for neonatal transfusions than currently transfused adult RBCs.
Post-collection, cord blood can be stored at room temperature for several days before it is processed for stem cells isolation, with little known about how these conditions affect currently discarded RBCs.
The present study examined the effect of the duration cord blood spent at room temperature and other cord blood characteristics on cord RBC quality.
RBCs were tested immediately after their isolation from cord blood using a broad panel of quality assays.
No significant decrease in cord RBC quality was observed during the first 65 hours of storage at room temperature.
The ratio of cord blood to anticoagulant was associated with RBC quality and needs to be optimized in future.
This knowledge will assist in future development of cord RBC transfusion product.
American Psychological Association (APA)
Zhurova, Mariia& Akabutu, John& Acker, Jason P.. 2012. Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature. Journal of Blood Transfusion،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-446507
Modern Language Association (MLA)
Zhurova, Mariia…[et al.]. Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature. Journal of Blood Transfusion No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-446507
American Medical Association (AMA)
Zhurova, Mariia& Akabutu, John& Acker, Jason P.. Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature. Journal of Blood Transfusion. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-446507
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446507