Synthesis, Spectroscopic Characterization, and In Vitro Antimicrobial Studies of Pyridine-2-Carboxylic Acid N′-(4-Chloro-Benzoyl)-Hydrazide and Its Co(II), Ni(II), and Cu(II) Complexes
Joint Authors
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
N-substituted pyridine hydrazide (pyridine-2-carbonyl chloride and 4-chloro-benzoic acid hydrazide) undergoes hydrazide formation of the iminic carbon nitrogen double bond through its reaction with cobalt(II), nickel(II), and copper(II) metal salts in ethanol which are reported and characterized based on elemental analyses, IR, solid reflectance, magnetic moment, molar conductance, and thermal analysis (TG).
From the elemental analyses data, 1 : 2 metal complexes are formed having the general formulae [MCl2(HL)2] · yH2O (where M = Co(II), Ni(II), and Cu(II), y = 1–3).
The important infrared (IR) spectral bands corresponding to the active groups in the ligand and the solid complexes under investigation were studied.
IR spectra show that ligand is coordinated to the metal ions in a neutral bidentate manner with ON donor sites.
The solid complexes have been synthesized and studied by thermogravimetric analysis.
All the metal chelates are found to be nonelectrolytes.
From the magnetic and solid reflectance spectra, the complexes (cobalt(II), nickel(II), and copper(II)) have octahedral and square planner geometry, respectively.
The antibacterial and antifungal activity’s data show that the metal complexes have a promising biological activity comparable with the parent ligand against bacterial and fungal species.
American Psychological Association (APA)
Singh, Jagvir& Singh, Prashant. 2012. Synthesis, Spectroscopic Characterization, and In Vitro Antimicrobial Studies of Pyridine-2-Carboxylic Acid N′-(4-Chloro-Benzoyl)-Hydrazide and Its Co(II), Ni(II), and Cu(II) Complexes. Bioinorganic Chemistry and Applications،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-446689
Modern Language Association (MLA)
Singh, Jagvir& Singh, Prashant. Synthesis, Spectroscopic Characterization, and In Vitro Antimicrobial Studies of Pyridine-2-Carboxylic Acid N′-(4-Chloro-Benzoyl)-Hydrazide and Its Co(II), Ni(II), and Cu(II) Complexes. Bioinorganic Chemistry and Applications No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-446689
American Medical Association (AMA)
Singh, Jagvir& Singh, Prashant. Synthesis, Spectroscopic Characterization, and In Vitro Antimicrobial Studies of Pyridine-2-Carboxylic Acid N′-(4-Chloro-Benzoyl)-Hydrazide and Its Co(II), Ni(II), and Cu(II) Complexes. Bioinorganic Chemistry and Applications. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-446689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446689