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Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs
Joint Authors
Lovett-Racke, Amy E.
Racke, Michael K.
Yang, Yuhong
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
PPARs are members of the steroid hormone nuclear receptor superfamily and play an important role in regulating inflammation as well as lipid metabolism.
The PPAR subfamily has been defined as PPARα, PPARβ/δ, and PPARγ, each with different ligands, target genes, and biological roles.
PPARs regulate the expression of target inflammatory genes through mechanisms involving both transactivation and transrepression.
The anti-inflammatory properties of PPAR agonists have led to the investigation of PPAR functions in regulating autoimmune encephalomyelitis.
This paper will summarize some of the general mechanisms by which PPARs regulate inflammatory gene expression and focus on the recent advances of PPAR regulation of autoimmune encephalomyelitis.
American Psychological Association (APA)
Yang, Yuhong& Lovett-Racke, Amy E.& Racke, Michael K.. 2010. Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs. PPAR Research،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-446706
Modern Language Association (MLA)
Yang, Yuhong…[et al.]. Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs. PPAR Research No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-446706
American Medical Association (AMA)
Yang, Yuhong& Lovett-Racke, Amy E.& Racke, Michael K.. Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs. PPAR Research. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-446706
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446706