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Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery
Joint Authors
Carrillo-Alarcón, Lourdes
Reyes-García, Gerardo
Ortiz, Mario I.
Soto-Ríos, Marisela
Monroy-Maya, Raúl
Ponce-Monter, Héctor A.
Garza-Hernández, Alexis F.
Fernández-Martínez, Eduardo
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The aim of this study was to compare the efficacy of diclofenac, for the treatment of acute pain originated by lower-limb fracture and surgery, with that of diclofenac plus B vitamins.
This was a single-center, prospective, randomized, and double-blinded clinical trial.
Patients with lower-limb closed fractures rated their pain on a 10 cm visual analog scale (VAS).
Patients were then randomized to receive diclofenac or diclofenac plus B vitamins (thiamine, pyridoxine, and cyanocobalamin) intramuscularly twice daily.
Patient evaluations of pain intensity were recorded throughout two periods: twenty-four hours presurgery and twenty-four hours postsurgical.
One hundred twenty-two patients completed the study.
The subjects' assessments of limb pain on the VAS showed a significant reduction from baseline values regardless of the treatment group.
Diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone.
The results showed that the addition of B vitamins to diclofenac increased its analgesic effect.
The novelty of this paper consists in that diclofenac and diclofenac plus B vitamins were useful for treatment of acute pain originated by lower-limb fracture and surgery.
American Psychological Association (APA)
Ponce-Monter, Héctor A.& Ortiz, Mario I.& Garza-Hernández, Alexis F.& Monroy-Maya, Raúl& Soto-Ríos, Marisela& Carrillo-Alarcón, Lourdes…[et al.]. 2011. Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery. Pain Research and Treatment،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-446713
Modern Language Association (MLA)
Ponce-Monter, Héctor A.…[et al.]. Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery. Pain Research and Treatment No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-446713
American Medical Association (AMA)
Ponce-Monter, Héctor A.& Ortiz, Mario I.& Garza-Hernández, Alexis F.& Monroy-Maya, Raúl& Soto-Ríos, Marisela& Carrillo-Alarcón, Lourdes…[et al.]. Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery. Pain Research and Treatment. 2011. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-446713
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446713