Relationships between Plasma Micronutrients, Serum IgE, and Skin Test Reactivity and Asthma among School Children in Rural Southwest Nigeria
Joint Authors
Oluwole, Oluwafemi
Adu, Mary D.
Olopade, Christopher O.
Arinola, Olatunbosun G.
Adepoju, Adedayo
Adedokun, Babatunde O.
Olopade, Olufunmilayo I.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
Increasing prevalence of asthma has been attributed to changes in lifestyle and environmental exposures.
We conducted a case-control study to investigate the relationship between serum micronutrients and asthma in rural school children in Nigeria.
Methods.
We administered questionnaires to 1,562 children to identify children with asthma.
Serum concentration levels of 12 micronutrients were determined in asthma cases (N=37) and controls (N=30).
Allergy skin prick test and spirometry were also performed.
Results.
Plasma levels of the following micronutrients were significantly different between cases and controls: calcium (7.48±2.16 versus 8.29±1.62 mg/dL; P=0.04), manganese (44.1±11.5 versus 49.3±7.9 mg/L; P=0.01), selenium (76.1±14.9 versus 63.3±26.8 μg/L; P=0.02), and albumin (3.45±0.90 versus 3.91±0.99 g/dL; P=0.04).
Plasma concentrations of iron and selenium were positively correlated with lung function, r=0.43 (P<0.05 in each case) while manganese serum concentration was negatively correlated with asthma (r=-0.44; P<0.05).
Conclusions.
Children with asthma had reduced levels of plasma manganese, calcium, and albumin but raised level of selenium.
The protective or risk effects of these micronutrients on asthma warrant further investigation.
American Psychological Association (APA)
Oluwole, Oluwafemi& Arinola, Olatunbosun G.& Adu, Mary D.& Adepoju, Adedayo& Adedokun, Babatunde O.& Olopade, Olufunmilayo I.…[et al.]. 2014. Relationships between Plasma Micronutrients, Serum IgE, and Skin Test Reactivity and Asthma among School Children in Rural Southwest Nigeria. Journal of Biomarkers،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-446836
Modern Language Association (MLA)
Oluwole, Oluwafemi…[et al.]. Relationships between Plasma Micronutrients, Serum IgE, and Skin Test Reactivity and Asthma among School Children in Rural Southwest Nigeria. Journal of Biomarkers No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-446836
American Medical Association (AMA)
Oluwole, Oluwafemi& Arinola, Olatunbosun G.& Adu, Mary D.& Adepoju, Adedayo& Adedokun, Babatunde O.& Olopade, Olufunmilayo I.…[et al.]. Relationships between Plasma Micronutrients, Serum IgE, and Skin Test Reactivity and Asthma among School Children in Rural Southwest Nigeria. Journal of Biomarkers. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-446836
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446836