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Synthesis and Antimicrobial Activities of Some New Synthesized Imide and Schiff's Base Derivatives
Joint Authors
Flefel, Eman M.
Amr, Abd El-Galil E.
al-Omar, Mohamed A.
Sabry, Nermien M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A series of 2,6-bis(substituted thiazolopyrimi-dinyl) pyridine (2a,b) and corresponding Schiff's bases (3a–j) were synthesized from 2,6-bis-(3-amino-2-methyl-4-oxo-9-substituted-3,4-dihydropyrido-[30,20 : 4,5]-thieno[3,2-d]pyrimidin-7-yl)pyridines (1a,b) as starting materials.
The compounds 1a,b were reacted with 2,3,4,5-tetrachlorophthalic anhydride in glacial acetic acid to give the corresponding bis-imides (2a,b).
But they are treated with aromatic aldehydes in refluxing ethanol to afford the Schiff’s base derivatives (3a–j).
The antimicrobial screening showed that many of these newly synthesized compounds had good antimicrobial activities comparable to streptomycin and fusidic acid as positive controls.
The detailed synthesis, spectroscopic data, and antimicrobial activities of the synthesized compounds were reported.
American Psychological Association (APA)
Sabry, Nermien M.& Flefel, Eman M.& al-Omar, Mohamed A.& Amr, Abd El-Galil E.. 2012. Synthesis and Antimicrobial Activities of Some New Synthesized Imide and Schiff's Base Derivatives. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-446893
Modern Language Association (MLA)
Sabry, Nermien M.…[et al.]. Synthesis and Antimicrobial Activities of Some New Synthesized Imide and Schiff's Base Derivatives. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-446893
American Medical Association (AMA)
Sabry, Nermien M.& Flefel, Eman M.& al-Omar, Mohamed A.& Amr, Abd El-Galil E.. Synthesis and Antimicrobial Activities of Some New Synthesized Imide and Schiff's Base Derivatives. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-446893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446893