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Nanostructured Mesoporous Silicas for Bone Tissue Regeneration
Joint Authors
Colilla, Montserrat
Vallet-Regí, María
Izquierdo-Barba, Isabel
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-11-04
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The research on the development of new biomaterials that promote bone tissue regeneration is receiving great interest by the biomedical scientific community.
Recent advances in nanotechnology have allowed the design of materials with nanostructure similar to that of natural bone.
These materials can promote new bone formation by inducing the formation of nanocrystalline apatites analogous to the mineral phase of natural bone onto their surfaces, i.e.
they are bioactive.
They also stimulate osteoblast proliferation and differentiation and, therefore, accelerate the healing processes.
Silica-based ordered mesoporous materials are excellent candidates to be used as third generation bioceramics that enable the adsorption and local control release of biological active agents that promote bone regeneration.
This local delivery capability together with the bioactive behavior of mesoporous silicas opens up promising expectations in the bioclinical field.
In this review, the last advances in nanochemistry aimed at designing and tailoring the chemical and textural properties of mesoporous silicas for biomedical applications are described.
The recent developed strategies to synthesize bioactive glasses with ordered mesopore arrangements are also summarized.
Finally, a deep discussion about the influence of the textural parameters and organic modification of mesoporous silicas on molecules adsorption and controlled release is performed.
American Psychological Association (APA)
Izquierdo-Barba, Isabel& Colilla, Montserrat& Vallet-Regí, María. 2008. Nanostructured Mesoporous Silicas for Bone Tissue Regeneration. Journal of Nanomaterials،Vol. 2008, no. 2008, pp.1-14.
https://search.emarefa.net/detail/BIM-446914
Modern Language Association (MLA)
Izquierdo-Barba, Isabel…[et al.]. Nanostructured Mesoporous Silicas for Bone Tissue Regeneration. Journal of Nanomaterials No. 2008 (2008), pp.1-14.
https://search.emarefa.net/detail/BIM-446914
American Medical Association (AMA)
Izquierdo-Barba, Isabel& Colilla, Montserrat& Vallet-Regí, María. Nanostructured Mesoporous Silicas for Bone Tissue Regeneration. Journal of Nanomaterials. 2008. Vol. 2008, no. 2008, pp.1-14.
https://search.emarefa.net/detail/BIM-446914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446914