Vertebral Column Metastases from an Esthesioneuroblastoma : Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup
Joint Authors
Johnson, J. Patrick
Strickland, Allison S.
Shirzadi, Ali S.
Drazin, Doniel G.
Bannykh, Serguei I.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Esthesioneuroblastoma (ENB) is an uncommon aggressive malignant intranasal neoplasm that originates from neural crest cells of the olfactory epithelium.
Although local invasion to the sinuses is common, spinal metastasis of ENB is rare with only 28 documented cases involving the spine spinal cord, or leptomeninges.
We report a case of ENB with multiple drop metastases to the cervical and thoracic spine, and review the patient’s disease, medical history, and multiple interventions during a span of 15 years following the initial cranial resection.
Despite aggressive multiple surgical resections, radiation, and chemotherapy, the tumor had significant progression and recurrence.
The literature is reviewed, followed by a discussion of the natural progression of the disease and various reported interventions.
Although a combination of surgery with chemotherapy and radiation therapy has been recommended, no definitive management has been established for ENB.
Further research is needed to determine decisive treatment for metastatic ENB to the spine.
American Psychological Association (APA)
Shirzadi, Ali S.& Drazin, Doniel G.& Strickland, Allison S.& Bannykh, Serguei I.& Johnson, J. Patrick. 2013. Vertebral Column Metastases from an Esthesioneuroblastoma : Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup. Case Reports in Surgery،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-446963
Modern Language Association (MLA)
Shirzadi, Ali S.…[et al.]. Vertebral Column Metastases from an Esthesioneuroblastoma : Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup. Case Reports in Surgery No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-446963
American Medical Association (AMA)
Shirzadi, Ali S.& Drazin, Doniel G.& Strickland, Allison S.& Bannykh, Serguei I.& Johnson, J. Patrick. Vertebral Column Metastases from an Esthesioneuroblastoma : Chemotherapy, Radiation, and Resection for Recurrence with 15-Year Followup. Case Reports in Surgery. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-446963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446963