Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents : The Translational Experience
Joint Authors
Rothrock, Robert J.
Bruce, Jeffrey N.
Canoll, Peter
Yun, Jonathan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Recent improvements in the understanding of glioblastoma (GBM) have allowed for increased ability to develop specific, targeted therapies.
In parallel, however, there is a need for effective methods of delivery to circumvent the therapeutic obstacles presented by the blood-brain barrier and systemic side effects.
The ideal delivery system should allow for adequate targeting of the tumor while minimizing systemic exposure, applicability across a wide range of potential therapies, and have existing safe and efficacious systems that allow for widespread application.
Though many alternatives to systemic delivery have been developed, this paper will focus on our experience with convection-enhanced delivery (CED) and our focus on translating this technology from pre-clinical studies to the treatment of human GBM.
American Psychological Association (APA)
Yun, Jonathan& Rothrock, Robert J.& Canoll, Peter& Bruce, Jeffrey N.. 2013. Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents : The Translational Experience. Journal of Drug Delivery،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-446987
Modern Language Association (MLA)
Yun, Jonathan…[et al.]. Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents : The Translational Experience. Journal of Drug Delivery No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-446987
American Medical Association (AMA)
Yun, Jonathan& Rothrock, Robert J.& Canoll, Peter& Bruce, Jeffrey N.. Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents : The Translational Experience. Journal of Drug Delivery. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-446987
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446987