Improving the Safety of Tolerance Induction : Chimerism and Cellular Co-Treatment Strategies Applied to Vascularized Composite Allografts
Joint Authors
Wallace, Christopher Glenn
Wei, Fu-Chan
Liao, Shuen-Kuei
Huang, Wei-Chao
Lin, Jeng-Yee
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Although vascularized composite allografts (VCAs) have been performed clinically for a variety of indications, potential complications from long-term immunosuppression and graft-versus-host disease remain important barriers to widespread applications.
Recently it has been demonstrated that VCAs incorporating a vascularized long bone in a rat model provide concurrent vascularized bone marrow transplantation that, itself, functions to establish hematopoietic chimerism and donor-specific tolerance following non-myeloablative conditioning of recipients.
Advances such as this, which aim to improve the safety profile of tolerance induction, will help usher in an era of wider clinical VCA application for nonlife-saving reconstructions.
American Psychological Association (APA)
Huang, Wei-Chao& Lin, Jeng-Yee& Wallace, Christopher Glenn& Wei, Fu-Chan& Liao, Shuen-Kuei. 2012. Improving the Safety of Tolerance Induction : Chimerism and Cellular Co-Treatment Strategies Applied to Vascularized Composite Allografts. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-447010
Modern Language Association (MLA)
Huang, Wei-Chao…[et al.]. Improving the Safety of Tolerance Induction : Chimerism and Cellular Co-Treatment Strategies Applied to Vascularized Composite Allografts. Clinical and Developmental Immunology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-447010
American Medical Association (AMA)
Huang, Wei-Chao& Lin, Jeng-Yee& Wallace, Christopher Glenn& Wei, Fu-Chan& Liao, Shuen-Kuei. Improving the Safety of Tolerance Induction : Chimerism and Cellular Co-Treatment Strategies Applied to Vascularized Composite Allografts. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-447010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447010