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Physiopathology of Spine Metastasis
Joint Authors
Perisano, Carlo
Mauro, Sigismondo
Graci, Calogero
Maccauro, Giulio
Rosa, Michele Attilio
Spinelli, Maria Silvia
Source
International Journal of Surgical Oncology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The metastasis is the spread of cancer from one part of the body to another.
Two-thirds of patients with cancer will develop bone metastasis.
Breast, prostate and lung cancer are responsible for more than 80% of cases of metastatic bone disease.
The spine is the most common site of bone metastasis.
A spinal metastasis may cause pain, instability and neurological injuries.
The diffusion through Batson venous system is the principal process of spinal metastasis, but the dissemination is possible also through arterial and lymphatic system or by contiguity.
Once cancer cells have invaded the bone, they produce growth factors that stimulate osteoblastic or osteolytic activity resulting in bone remodeling with release of other growth factors that lead to a vicious cycle of bone destruction and growth of local tumour.
American Psychological Association (APA)
Maccauro, Giulio& Spinelli, Maria Silvia& Mauro, Sigismondo& Perisano, Carlo& Graci, Calogero& Rosa, Michele Attilio. 2011. Physiopathology of Spine Metastasis. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-447018
Modern Language Association (MLA)
Maccauro, Giulio…[et al.]. Physiopathology of Spine Metastasis. International Journal of Surgical Oncology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-447018
American Medical Association (AMA)
Maccauro, Giulio& Spinelli, Maria Silvia& Mauro, Sigismondo& Perisano, Carlo& Graci, Calogero& Rosa, Michele Attilio. Physiopathology of Spine Metastasis. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-447018
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447018