Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo
Joint Authors
De, Sachinandan
Brahma, Biswajit
Singh, Raj Kumar
Source
Molecular Biology International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The present study was conducted to study the diversity of MHC-DRB3 alleles in Indian cattle and buffalo breeds.
Previously reported BoLA-DRB exon 2 alleles of Indian Zebu cattle, Bos taurus cattle, buffalo, sheep, and goats were analyzed for the identities and divergence among various allele sequences.
Comparison of predicted amino acid residues of DRB3 exon 2 alleles with similar alleles from other ruminants revealed considerable congruence in amino acid substitution pattern.
These alleles showed a high degree of nucleotide and amino acid polymorphism at positions forming peptide-binding regions.
A higher rate of nonsynonymous substitution was detected at the peptide-binding regions, indicating that BoLA-DRB3 allelic sequence evolution was driven by positive selection.
American Psychological Association (APA)
De, Sachinandan& Singh, Raj Kumar& Brahma, Biswajit. 2011. Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo. Molecular Biology International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-447213
Modern Language Association (MLA)
De, Sachinandan…[et al.]. Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo. Molecular Biology International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-447213
American Medical Association (AMA)
De, Sachinandan& Singh, Raj Kumar& Brahma, Biswajit. Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo. Molecular Biology International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-447213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447213
