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In Vitro Evaluation of Antiprotozoal and Antiviral Activities of Extracts from Argentinean Mikania Species
Joint Authors
Malchiodi, Emilio
Sülsen, Valeria P.
Giberti, Gustavo
Martino, Virginia S.
Cavallaro, Lucía
Frank, Fernanda M.
Cazorla, Silvia I.
Laurella, Laura C.
Catalán, César A. N.
Alonso, María R.
Sarquiz, Andrea
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The aim of this study was to investigate the antiprotozoal and antiviral activities of four Argentinean Mikania species.
The organic and aqueous extracts of Mikania micrantha, M.
parodii, M.
periplocifolia, and M.
cordifolia were tested on Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes, and dengue virus type 2.
The organic extract of M.
micrantha was the most active against T.
cruzi and L.
braziliensis exhibiting a growth inhibition of 77.6±4.5% and 84.9±6.1%, respectively, at a concentration of 10 μg/ml.
The bioguided fractionation of M.
micrantha organic extract led to the identification of two active fractions.
The chromatographic profile and infrared analysis of these fractions revealed the presence of sesquiterpene lactones.
None of the tested extracts were active against dengue virus type 2.
American Psychological Association (APA)
Laurella, Laura C.& Frank, Fernanda M.& Sarquiz, Andrea& Alonso, María R.& Giberti, Gustavo& Cavallaro, Lucía…[et al.]. 2012. In Vitro Evaluation of Antiprotozoal and Antiviral Activities of Extracts from Argentinean Mikania Species. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447304
Modern Language Association (MLA)
Laurella, Laura C.…[et al.]. In Vitro Evaluation of Antiprotozoal and Antiviral Activities of Extracts from Argentinean Mikania Species. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-447304
American Medical Association (AMA)
Laurella, Laura C.& Frank, Fernanda M.& Sarquiz, Andrea& Alonso, María R.& Giberti, Gustavo& Cavallaro, Lucía…[et al.]. In Vitro Evaluation of Antiprotozoal and Antiviral Activities of Extracts from Argentinean Mikania Species. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447304
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447304