Vitamin D Signaling in Myogenesis : Potential for Treatment of Sarcopenia
Joint Authors
Wagatsuma, Akira
Sakuma, Kunihiro
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Muscle mass and strength progressively decrease with age, which results in a condition known as sarcopenia.
Sarcopenia would lead to physical disability, poor quality of life, and death.
Therefore, much is expected of an effective intervention for sarcopenia.
Epidemiologic, clinical, and laboratory evidence suggest an effect of vitamin D on muscle function.
However, the precise molecular and cellular mechanisms remain to be elucidated.
Recent studies suggest that vitamin D receptor (VDR) might be expressed in muscle fibers and vitamin D signaling via VDR plays a role in the regulation of myoblast proliferation and differentiation.
Understanding how vitamin D signaling contributes to myogenesis will provide a valuable insight into an effective nutritional strategy to moderate sarcopenia.
Here we will summarize the current knowledge about the effect of vitamin D on skeletal muscle and myogenic cells and discuss the potential for treatment of sarcopenia.
American Psychological Association (APA)
Wagatsuma, Akira& Sakuma, Kunihiro. 2014. Vitamin D Signaling in Myogenesis : Potential for Treatment of Sarcopenia. BioMed Research International،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-447305
Modern Language Association (MLA)
Wagatsuma, Akira& Sakuma, Kunihiro. Vitamin D Signaling in Myogenesis : Potential for Treatment of Sarcopenia. BioMed Research International No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-447305
American Medical Association (AMA)
Wagatsuma, Akira& Sakuma, Kunihiro. Vitamin D Signaling in Myogenesis : Potential for Treatment of Sarcopenia. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-447305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447305