Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-13
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Age-associated endothelium dysfunction is a major risk factor for the development of cardiovascular diseases.
Endothelium-synthesized prostaglandins and thromboxane are local hormones, which mediate vasodilation and vasoconstriction and critically maintain vascular homeostasis.
Accumulating evidence indicates that the age-related changes in endothelial eicosanoids contribute to decline in endothelium function and are associated with pathological dysfunction.
In this review we summarize currently available information on aging-shifted prostaglandin profiles in endothelium and how these shifts are associated with cardiovascular disorders, providing one molecular mechanism of age-associated endothelium dysfunction and cardiovascular diseases.
American Psychological Association (APA)
Qian, Hao& Luo, Na& Chi, Yuling. 2012. Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders. Journal of Aging Research،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-447318
Modern Language Association (MLA)
Qian, Hao…[et al.]. Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders. Journal of Aging Research No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-447318
American Medical Association (AMA)
Qian, Hao& Luo, Na& Chi, Yuling. Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders. Journal of Aging Research. 2012. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-447318
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447318