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Different Effects of Six Antibiotics and Ten Traditional Chinese Medicines on Shiga Toxin Expression by Escherichia coli O157 : H7
Joint Authors
Chen, Mei Ling
Hao, Zhao
Zhang, Qi Yao
Tian, Yuan
Jin, Jian Ling
Gao, Pei Ji
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study compared the effects of ten types of traditional Chinese medicines (TCMs) and six different antibiotics on E.
coli O157:H7 Shiga toxin gene (stx2) mRNA expression level based on real-time PCR and the expression level of Stx toxin using an ELISA quantitative assay.
We also compared their effects on the induction of the SOS response.
The results clearly indicated that all ten TCMs had negative results in the SOS response induction test, while most TCMs did not increase the levels of stx2 mRNA and the Stx toxin.
Some TCMs did increase the mRNA levels of the stx2 gene and the Stx toxin level, but their increases were much lower than those caused by antibiotics.
With the exception of cefotaxime, the six antibiotics increased the Stx toxin level and increased the stx2 gene mRNA level.
With the exceptions of cefotaxime and tetracycline, the antibiotics increased the SOS induction response.
These results suggest that TCMs may have advantages compared with antibiotics, when treating E.
coli O157:H7; TCMs did not greatly increase Stx toxin production and release.
American Psychological Association (APA)
Chen, Mei Ling& Hao, Zhao& Tian, Yuan& Zhang, Qi Yao& Gao, Pei Ji& Jin, Jian Ling. 2013. Different Effects of Six Antibiotics and Ten Traditional Chinese Medicines on Shiga Toxin Expression by Escherichia coli O157 : H7. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447321
Modern Language Association (MLA)
Chen, Mei Ling…[et al.]. Different Effects of Six Antibiotics and Ten Traditional Chinese Medicines on Shiga Toxin Expression by Escherichia coli O157 : H7. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-447321
American Medical Association (AMA)
Chen, Mei Ling& Hao, Zhao& Tian, Yuan& Zhang, Qi Yao& Gao, Pei Ji& Jin, Jian Ling. Different Effects of Six Antibiotics and Ten Traditional Chinese Medicines on Shiga Toxin Expression by Escherichia coli O157 : H7. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447321
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447321