Comparison of Characteristics of Connective Tissue Disease-Associated Interstitial Lung Diseases, Undifferentiated Connective Tissue Disease-Associated Interstitial Lung Diseases, and Idiopathic Pulmonary Fibrosis in Chinese Han Population : A Retrospective Study

Abstract EN

Our study compared the prevalence and characteristics of patients with connective tissue disease-associated interstitial lung disease (CTD-ILD), undifferentiated connective tissue disease-associated interstitial lung disease (UCTD-ILD), or idiopathic pulmonary fibrosis (IPF) between January 2009 and December 2012 in West China Hospital, western China.

Patients who met the criteria for ILD were included and were assigned to CTD-ILD, UCTD-ILD, or IPF group when they met the criteria for CTD, UCTD, or IPF, respectively.

Clinical characteristics, laboratory tests, and high-resolution CT images were analyzed and compared among three groups.

203 patients were included, and all were Han nationality.

CTD-ILD was identified in 31%, UCTD-ILD in 32%, and IPF in 37%.

Gender and age differed among groups.

Pulmonary symptoms were more common in IPF, while extrapulmonary symptoms were more common in CTD-ILD and UCTD-ILD group.

Patients with CTD-ILD had more abnormal antibody tests than those of UCTD-ILD and IPF.

Little significance was seen in HRCT images among three groups.

A systematic evaluation of symptoms and serologic tests in patients with ILD can identify CTD-ILD, UCTD-ILD, and IPF.