Early Primary Biliary Cirrhosis : A New Association with Erythema Nodosum of Unknown Origin
Joint Authors
Dalekos, Georgios N.
Gatselis, Nikolaos K.
Zachou, Kalliopi
Source
Gastroenterology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-25
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Primary biliary cirrhosis (PBC) is associated with immune-mediated dermatologic disorders.
The association of PBC with erythema nodosum (EN) seems rare.
We report two females (42 and 44 years old) with low-grade fever, arthralgias, and elevated cholestatic enzymes in the first and fatigue in the second.
Patients were also suffering from typical EN lesions characterized by multiple erythematous, painful nodules over the anterior portions of their lower extremities.
Clinical and extensive laboratory work up excluded all known EN causes.
PBC diagnosis was established according to the cholestatic biochemical profile, anti-mitochondrial antibodies (AMA) positivity and liver histology (first), and AMA and antinuclear (ANA) PBC-specific antibodies (second).
Our report may suggest that PBC could be kept in mind in EN patients of unknown aetiology and particularly, when middle-aged female patients are affected.
In such cases a thorough evaluation for AMA and/or ANA PBC-specific antibodies could be helpful to achieve a correct and timely diagnosis.
American Psychological Association (APA)
Gatselis, Nikolaos K.& Zachou, Kalliopi& Dalekos, Georgios N.. 2010. Early Primary Biliary Cirrhosis : A New Association with Erythema Nodosum of Unknown Origin. Gastroenterology Research and Practice،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-447335
Modern Language Association (MLA)
Gatselis, Nikolaos K.…[et al.]. Early Primary Biliary Cirrhosis : A New Association with Erythema Nodosum of Unknown Origin. Gastroenterology Research and Practice No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-447335
American Medical Association (AMA)
Gatselis, Nikolaos K.& Zachou, Kalliopi& Dalekos, Georgios N.. Early Primary Biliary Cirrhosis : A New Association with Erythema Nodosum of Unknown Origin. Gastroenterology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-447335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447335